| Sunday, September 23, 2012 English Premier League | |||||
| Status | Home | Score | Away | Venue | |
| FT | Liverpool | 1-2 | Manchester United | Anfield (44,263) | |
| FT | Newcastle United | 1-0 | Norwich City | Sports Direct Arena (49,402) | |
| FT | Manchester City | 1-1 | Arsenal | Etihad Stadium (47,318) | |
| FT | Tottenham Hotspur | 2-1 | Queens Park Rangers | White Hart Lane (36,052) | |
| Sunday, September 23, 2012 English Champion League | |||||
| Status | Home | Score | Away | Venue | |
| FT | Leicester City | 3-1 | Hull City | The King Power Stadium (20,815) | |
| Sunday, September 23, 2012 Spanish Liga BBVA | |||||
| Status | Home | Score | Away | Venue | |
| FT | Mallorca | 2-0 | Valencia | Estadio Son Moix (15,000) | |
| FT | Levante | 2-1 | Real Sociedad | Ciudad de Valencia (16,000) | |
| FT | Atlético Madrid | 2-1 | Valladolid | Vicente Calderon (47,000) | |
| FT | Athletic Bilbao | 0-0 | Málaga | Estadio San Mamés (37,000) | |
| Sunday, September 23, 2012 Serie A Italy | |||||
| Status | Home | Score | Away | Venue | |
| FT | Sampdoria | 1-1 | Torino | Luigi Ferraris (22,000) | |
| FT | Atalanta | 1-0 | Palermo | Atleti Azzurri d'Italia (15,000) | |
| FT | Bologna | 1-1 | US Pescara | Renato Dall'Ara (19,000) | |
| Postp | Cagliari | P - P | AS Roma | Sant'Elia | |
| FT | Catania | 0-0 | Napoli | Angelo Massimino (15,000) | |
| FT | Internazionale | 0-2 | Siena | Stadio Giuseppe Meazza (44,000) | |
| FT | Udinese | 2-1 | AC Milan | Stadio Friuli (18,000) | |
| FT | Lazio | 0-1 | Genoa | Stadio Olimpico (31,000) | |
| Sunday, September 23, 2012 German Bundesliga | |||||
| Status | Home | Score | Away | Venue | |
| FT | Bayer Leverkusen | 1-1 | Borussia Monchengladbach | BayArena (27,640) | |
| FT | TSG Hoffenheim | 3-1 | Hannover 96 | Rhein-Neckar-Arena (23,575) | |
| FT | Werder Bremen | 2-2 | VfB Stuttgart | Weserstadion (40,172) | |
| Sunday, September 23, 2012 French Ligue 1 | |||||
| Status | Home | Score | Away | Venue | |
| FT | Bordeaux | 2-2 | AC Ajaccio | Stade Jacques Chaban-Delmas | |
| FT | Marseille | 1-0 | Evian Thonon Gaillard | Stade Vélodrome | |
| FT | Lille | 1-1 | Lyon | Grand Stade Lille Métropole | |